On episode 16, Unexpected, Simone Duveaux dies. I think she's going to come back.
Let's start with Simone's father, Charles Duveaux. Before he died he mentioned that he saw himself and Peter flying around the city. He didn't know that Peter could fly. Why would he have dreamed this? I think Charles has the power of visions. Peter, being around Charles, absorbed that power. That's why Peter is able to see visions (for example, of Nathan flying out of the car before it crashed). This is similar to but separate from Isaac's power of painting the future (which may be prediction or may be causing it—not sure!).
We also know that having a power is genetic (from Chandra's research), and that it's inherited (Micah, Claire, and that little girl that Matt saved). The specific power is not inherited, just that they have one.
Putting the two together, Simone very likely has a power.
What power would she have? She liked Isaac when he had a drug problem, and liked Peter when he was in trouble. She likes people in trouble. She wants to help them. I think her power involves helping others, perhaps healing them, perhaps projecting powers onto them. If it's the power of projection, her power probably is not of much use, since she has no other power to project. But when Peter absorbs that power, he might be able to project Claire's power of healing onto Simone. And that would bring Simone back from the dead.
Why am I convinced Simone should come back? Ignoring the Neo/Trinity to Peter/Simone parallel (did you see how Peter stopped bullets?), the main issue is that Simone was in Peter's future vision when Peter blows up. I think Isaac was pulling Simone away from Peter in that vision. So I think she needs to be alive. On the other hand, the visions are not predictions, and don't have to be taken literally. Charles's vision for example never came true; it was merely expressing the idea of flight, and the details weren't accurate.
While it's possible that Simone will stay dead, I'm betting Peter won't show up for several epsiodes, then he'll bring her back to life, and then she'll leave the storyline for other reasons.